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HCoV-OC43 Spike/S1 (HEK293, His)

Coronaviruses, enveloped positive-strand RNA viruses, generally cause mild to moderate upper-respiratory tract illness. OC43, like SARS-CoV-2, is in the genus Betacoronavirus but grouped in another subgenus called Embecovirus. The NS2 protein of HCoV-OC43 has cyclic phosphodiesterase activity, which may modulate cAMP-mediated signaling and important physiological processes such as lipid metabolism and apoptosis. HCoV-OC43 replicate principally in the upper respiratory tract epithelial cells, where they produce virus and cause local respiratory symptoms[1][2]. HCoV-OC43 Spike/S1 Protein (HEK293, His) is the recombinant Virus-derived HCoV-OC43 Spike/S1 protein, expressed by HEK293 , with C-His labeled tag.

Product Specifications

Product Name Alternative

HCoV-OC43 Spike/S1 Protein (HEK293, His), Virus, HEK293

UNSPSC

12352202

Type

Recombinant Proteins

Assay Protocol

https://www.medchemexpress.com/cytokines/hcov-oc43-spike-s1-protein-hek293-his.html

Molecular Formula

/ (Gene_ID) AVR40344 (M1-L794) (Accession)

Molecular Weight

Approximately 89.02 kDa.

References & Citations

[1]Ding X. Liu, et al. Human Coronavirus-229E, -OC43, -NL63, and -HKU1 (Coronaviridae) . Encyclopedia of Virology. 2021 : 428–440.|[2]Chunyan Wangm, et al. Antigenic structure of the human coronavirus OC43 spike reveals exposed and occluded neutralizing epitopes.

Shipping Conditions

Dry ice.

Scientific Category

Recombinant Proteins

Frequently Asked Questions

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