LGR5 Antibody (loop2)
Rabbit polyclonal antibody to LGR5 (Leucine-rich repeat G protein-coupled receptor 5) is thought of as a possible stem cell marker for the hair follicle and the epithelium of the intestine. LGR5 is only expressed in cycling crypt base columnar cells, which are thought to be genuine intestinal stem cells. LGR5 has also been implicated as a negative regulator of the Wnt signaling pathway. LGR5 is often up-regulated in certain cancers and may play a role in cancer cell progression.
Product Specifications
Product Name Alternative
UniProt
O75473
Reactivity
Human, Mouse, Rat
Immunogen
Synthetic Peptide
Target
LGR5
Clonality
Polyclonal
Conjugation
Unconjugated
Field of Research
Cancer Biology, Pharmacology & Drug Discovery, Signal Transduction
Dilution
WB - 1:1000, IF - 1:100, FC - 1:25
Form
Molecular Weight
99998
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Notes
For research use only.
Tested Applications
FC, WB
NCBI Accession Number
NP_003658.1, NP_001264155.1
Host or Source
Rabbit
Isotype
Rabbit IgG
Available Sizes
Frequently Asked Questions
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