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NGFR/p75 neurotrophin receptor (p75NTR) Antibody (Saporin)

Selected Variant

GTR18793189

Size: 25 µg

Our Anti-NGFR/p75 neurotrophin receptor (p75NTR) mouse monoclonal primary antibody detects rat NGFR/p75 neurotrophin receptor (p75NTR), and is purified. It is validated for use in-vivo.

Product Specifications

Product Name Alternative

Low-affinity nerve growth factor receptor; NGF receptor; Gp80-LNGFR; p75 ICD; Low affinity neurotrophin receptor p75NTR; CD271

UniProt

P20656, P07174

Reactivity

Rat

Immunogen

Rat NGF receptor (p75NTR)

Target

NGFR/p75 neurotrophin receptor (p75NTR)

Clonality

Monoclonal

Clone

MC192

Conjugation

Unconjugated

Purification

Purified

Form

Lyophilized

Storage Conditions

Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Notes

For research use only.

Applications Notes

1. To specifically target and eliminate rat cells expressing p75NTR in vivo. MC192-saporin has been used to selectively lesion cholinergic neurons of basal forebrain to create an animal model to study Alzheimer's disease. 2. To be used as a model for gene delivery into neurons.

Tested Applications

In vivo

Host or Source

Mouse

Preservative

Lyophilized from a 1 mg/mL solution containing PBS pH 7.2-7.6 without preservative.

Isotype

IgG1

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