α-Conotoxin PIA (TFA)
Product Specifications
UNSPSC Description
α-Conotoxin PIA TFA is a nicotinic acetylcholine receptor (nAChR) antagonist that targets nAChR subtypes containing α6 and α3 subunits. α-Conotoxin PIA has the potential for the research of Parkinson’s disease, and schizophrenia[1]。
Target Antigen
nAChR
Type
Peptides
Related Pathways
Membrane Transporter/Ion Channel;Neuronal Signaling
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Purity
99.81
Solubility
DMSO : ≥ 250 mg/mL
Smiles
O=C(N[C@@H](CC(O)=O)C(N1[C@@H](CCC1)C(N[C@@H](CSSC[C@@H](C(N[C@@H]([C@H](O)C)C(N[C@@H](C(C)C)C(N[C@@H](CC2=CNC=N2)C(N[C@@H](CC(N)=O)C(N3[C@@H](CCC3)C(N[C@@H](CCC(N)=O)C(N[C@H]4[C@@H](C)CC)=O)=O)=O)=O)=O)=O)=O)NC5=O)C(N[C@@H](CSSC[C@@H](C(N)=O)NC4=O)C(N[C@@H](CO)C(N[C@@H](CC(N)=O)C(N6[C@@H](CCC6)C(N[C@H]5C(C)C)=O)=O)=O)=O)=O)=O)=O)[C@H](CCCNC(N)=N)N.FC(C(O)=O)(F)F
Molecular Weight
2323.33
References & Citations
[1]Seung-Wook Chi , et al. Solution Structure of Alpha-Conotoxin PIA, a Novel Antagonist of alpha6 Subunit Containing Nicotinic Acetylcholine Receptors. Biochem Biophys Res Commun. 2005 Dec 30;338(4):1990-7.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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