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YK-2-69

Product Specifications

UNSPSC Description

YK-2-69 is a highly selective DYRK2 inhibitor with an IC50 value of 9 nM. YK-2-69 specifically interacts with Lys-231 and Lys-234 of DYRK2 and can be utilized in researches related to prostate cancer[1].

Target Antigen

DYRK

Type

Reference compound

Related Pathways

Protein Tyrosine Kinase/RTK

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/yk-2-69.html

Smiles

O=C(N1CCN(CC1)CC)C2=CN=C(NC3=NC(C4=CC5=C(N=C(N(C)C)S5)C=C4)=C(F)C=N3)C=C2

Molecular Weight

506.60

References & Citations

[1]Yuan K, et al. Targeting dual-specificity tyrosine phosphorylation-regulated kinase 2 with a highly selective inhibitor for the treatment of prostate cancer. Nat Commun. 2022 May 25;13(1):2903.

Shipping Conditions

Blue Ice

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-153949/YK-2-69-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-153949/YK-2-69-SDS-MedChemExpress.pdf

Clinical Information

No Development Reported

CAS Number

2619846‑89‑6

Available Sizes

Curated Selection

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