DCC Antibody (Center)
Rabbit polyclonal antibody to DCC also known as Tumor suppressor protein DCC whose expression can be detected in the mucus but it is majorly expressive in the axons and intestine. It is found in the axon. It can perform various functions like exogenesis and neuron migration. Its association with UNC5 proteins may trigger signaling for axon repulsion. It also acts as a dependence receptor required for apoptosis induction when not associated with the netrin ligand. Implicated as a tumor suppressor gene.
Product Specifications
Product Name Alternative
Anti-DCC antibody, anti-Netrin receptor DCC antibody, anti-IGDCC1 antibody
UniProt
P43146
Reactivity
Mouse
Immunogen
Synthetic Peptide
Target
DCC
Clonality
Polyclonal
Conjugation
Unconjugated
Field of Research
Cell Biology, Neuroscience
Dilution
WB - 1:1000, IHC-P - 1:10-50
Form
Molecular Weight
158457
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Notes
For research use only.
Prediction Reactivity
Rat
Tested Applications
IHC-P, WB
NCBI Accession Number
NP_005206.2
Host or Source
Rabbit
Isotype
Rabbit IgG
Available Sizes
Frequently Asked Questions
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