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Cephalin form bovine brain

Cephalin form bovine brain is an orally active phospholipid widely present in organisms.Cephalin form bovine brain participates in the formation of autophagosome membrane as a lipid anchor of autophagy-related protein Atg8/LC3. Cephalin form bovine brain enhances Autophagic flux, promotes cell differentiation, regulates lipid droplet fusion, delays aging, and also affects lipid metabolism and membrane integrity[1][2][3][4][5][6][7].

Product Specifications

CAS Number

90989-93-8

UNSPSC

12352200

Hazard Statement

H301-H311-H331

Target

Autophagy; Liposome

Type

Biochemical Assay Reagents

Related Pathways

Autophagy; Metabolic Enzyme/Protease

Field of Research

Metabolic Disease; Neurological Disease

Assay Protocol

https://www.medchemexpress.com/phosphatidylethanolamine.html

Purity

98.0

Solubility

DMSO : 5 mg/mL (ultrasonic) |Ethanol : 50 mg/mL (ultrasonic)

Smiles

[Cephalinformbovinebrain]

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P361+P364-P403+P233-P405-P501

References & Citations

[1]Rockenfeller P, et al. Phosphatidylethanolamine positively regulates autophagy and longevity. Cell Death Differ. 2015 Mar;22 (3) :499-508. |[2]Ishigamori H, et al. Docosahexaenoic acid-containing phosphatidylethanolamine enhances HL-60 cell differentiation by regulation of c-jun and c-myc expression. Mol Cell Biochem. 2005 Jul;275 (1-2) :127-33. |[3]Cohen BC, et al. Lipid Droplet Fusion in Mammary Epithelial Cells is Regulated by Phosphatidylethanolamine Metabolism. J Mammary Gland Biol Neoplasia. 2017 Dec;22 (4) :235-249.|[4]Wellner N, et al. Studies on the anorectic effect of N-acylphosphatidylethanolamine and phosphatidylethanolamine in mice. Biochim Biophys Acta. 2011 Sep;1811 (9) :508-12.|[5]Li Z, et al. The ratio of phosphatidylcholine to phosphatidylethanolamine influences membrane integrity and steatohepatitis. Cell Metab. 2006 May;3 (5) :321-31. |[6]Imaizumi K, et al. The contrasting effect of dietary phosphatidylethanolamine and phosphatidylcholine on serum lipoproteins and liver lipids in rats. J Nutr. 1983 Dec;113 (12) :2403-11.|[7]Imaizumi K, et al. Effect of phosphatidylethanolamine and its constituent base on the metabolism of linoleic acid in rat liver. Biochim Biophys Acta. 1989 Oct 17;1005 (3) :253-9.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Biochemical Assay Reagents

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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