PARP10-IN-3
PARP10-IN-3 is a selective mono‐ADP‐ribosyltransferase PARP10 inhibitor with an IC50 of 480 nM for human PARP10. PARP10-IN-3 reveals potent inhibition on PARP2 and PARP15 with IC50s of 1.7 μM for human PARP2 and human PARP15, respectively[1].
Product Specifications
CAS Number
[2225800-19-9]
UNSPSC
12352005
Hazard Statement
H302, H315, H319
Target
PARP
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Epigenetics
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/parp10-in-3.html
Purity
98.72
Solubility
DMSO : 50 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=C(C1=CC=C(C=C1)OC2=CC=CC(C(N)=O)=C2)N
Molecular Formula
C14H12N2O3
Molecular Weight
256.26
Precautions
H302, H315, H319
References & Citations
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
PARP1; PARP10; PARP12; PARP14; PARP15; PARP16; PARP2; PARP3; PARP4; TNKS1/PARP5A; TNKS2/PARP5B
Available Sizes
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