ALKBH5-IN-3
Product Specifications
UNSPSC Description
ALKBH5-IN-3 (Compound 20m) is a potent and selective ALKBH5 inhibitor, with an IC50 of 21 nM. ALKBH5-IN-3 could efficiently stabilize ALKBH5 in HepG2 cells and increase m6A level in intact cells[1].
Target Antigen
Others
Type
Reference compound
Related Pathways
Others
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/alkbh5-in-3.html
Smiles
O=C(C1=NN(C2=CC=CC(C(F)(F)F)=C2)C(O)=C1)O
Molecular Weight
272.18
References & Citations
[1]Fang Z, et, al. Discovery of a potent, selective and cell active inhibitor of m6A demethylase ALKBH5. Eur J Med Chem. 2022 Aug 5:238:114446.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-165422/ALKBH5-IN-3-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-165422/
Clinical Information
No Development Reported
CAS Number
1505579-77-0
Available Sizes
Curated Selection
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