WSF1-IN-1
WSF1-IN-1 (compound 136), an orally active WSF1 inhibitor, can be used in the study for WSF1 (Wolfram syndrome) related tumors, with IC50 values of 0.33 μM and >27 μM in HepG2 parental and HepG2 WFS1 KO cell lines, respectively[1].
Product Specifications
CAS Number
[2379577-82-7]
UNSPSC
12352005
Target
Transmembrane Glycoprotein
Type
Reference compound
Related Pathways
Immunology/Inflammation
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/wsf1-in-1.html
Purity
99.91
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
CN([C@H]1C)C2=NC(NCC(C=N3)=CN3CC(C=C4)=CN=C4C(F)(F)F)=NC(C)=C2NC1=O
Molecular Formula
C20H21F3N8O
Molecular Weight
446.43
References & Citations
[1]Lauffer, David J, et al. Preparation of pyridine compass. for the treatment of cellular proliferative disorders. US 20190322673 A1.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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