CTPB

CTPB is a good activator of p300 histone acetyl transferase (HAT) enzyme[1].

Product Specifications

CAS Number

[586976-24-1]

UNSPSC

12352005

Hazard Statement

H302, H315, H319

Target

Histone Acetyltransferase

Type

Reference compound

Related Pathways

Epigenetics

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/CTPB.html

Purity

99.0

Solubility

DMSO : 62.5 mg/mL (ultrasonic)

Smiles

O=C(NC1=CC=C(Cl)C(C(F)(F)F)=C1)C2=C(CCCCCCCCCCCCCCC)C=CC=C2OCC

Molecular Formula

C31H43ClF3NO2

Molecular Weight

554.13

Precautions

H302, H315, H319

References & Citations

[1]Sivanandam M, et al. Investigation of activation mechanism and conformational stability of N- (4-chloro-3-trifluoromethyl-phenyl) -2-ethoxybenzamide and N- (4-chloro-3-trifluoromethyl-phenyl) -2-ethoxy-6-pentadecyl-benzamidein the active site of p300 histone acetyl transferase enzyme by molecular dynamics and binding free-energy studies. J Biomol Struct Dyn. 2018 Oct 9:1-38.