NR4A agonist-1
NR4A agonist-1, a fatty acid mimetic (FAM), is a potent NR4A agonist. NR4A agonist-1 exhibits high agonist potency on NR4A receptors Nurr1, Nur77, and NOR-1, with EC50s of 0.09 μM, 0.04 μM, and 0.15 μM, respectively[1].
Product Specifications
CAS Number
[360778-55-8]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Nuclear Hormone Receptor 4A/NR4A
Type
Reference compound
Related Pathways
Vitamin D Related/Nuclear Receptor
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/nurr1-agonist-8.html
Purity
99.93
Solubility
DMSO : 125 mg/mL (ultrasonic)
Smiles
O=C(C1=CC(OCC2=CC=C(C=C2Cl)Cl)=CC=C1)O
Molecular Formula
C14H10Cl2O3
Molecular Weight
297.13
Precautions
H302, H315, H319, H335
References & Citations
[1]Stiller T, et al. Exploring Fatty Acid Mimetics as NR4A Ligands. J Med Chem. 2023 Nov 2
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
