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Pentiapine

Pentiapine (CGS 10746) is a dopamine release inhibitor without binding to synaptic dopamine receptor sites[1][2].

Product Specifications

CAS Number

81382-51-6

Product Name Alternative

CGS 10746

UNSPSC

12352005

Target

Dopamine Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/Pentiapine.html

Purity

99.95

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

CN1CCN(C2=NC3=CC=CC=C3SC4=NC=CN42)CC1

Molecular Formula

C15H17N5S

Molecular Weight

299.39

References & Citations

[1]Manzanedo C, et al. Effects of CGS 10746B on hyperactivity and place preference induced by morphine. Behav Brain Res. 2001 Nov 29;126 (1-2) :23-32.|[2]Bilsky EJ, et al. CGS 10746B, a novel dopamine release inhibitor, blocks the establishment of cocaine and MDMA conditioned place preferences. Pharmacol Biochem Behav. 1998 Jan;59 (1) :215-20.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, protect from light)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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