ML 2-14
Product Specifications
UNSPSC Description
ML 2-14 is a PROTAC for degrading BRD4, with C4 alkyl linker. ML 2-14 exerts degradation of BRD4 in 231MFP breast cancer cells[1].
Target Antigen
PROTAC Linkers
Type
Reference compound
Related Pathways
PROTAC
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/ml-2-14.html
Smiles
ClC1=CC=C(C=C1)C2=N[C@@H](CC(NCCCCOC3=CC=C(C4CC(C5=CC=C(Br)C=C5)=NN4C(CCl)=O)C=C3)=O)C6=NN=C(C)N6C7=C2C(C)=C(C)S7
Molecular Weight
847.65
References & Citations
[1]Luo M, et al. Chemoproteomics-enabled discovery of covalent RNF114-based degraders that mimic natural product function. Cell Chem Biol. 2021;28(4):559-566.e15.
Shipping Conditions
Room Temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-132991/ML-2-14-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-132991/ML-2-14-SDS-MedChemExpress.pdf
Available Sizes
Curated Selection
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