20-HETE Ethanolamide

20-HETE Ethanolamide is a metabolite of endocannabinoid Anandamide. 20-HETE Ethanolamide binds to the rat brain cannabinoid CB1 receptor with a Ki of 985 nM[1][2].

Product Specifications

CAS Number

[942069-11-6]

UNSPSC

12352211

Hazard Statement

H225-H319

Target

Endogenous Metabolite

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/20-hete-ethanolamide.html

Solubility

10 mM in DMSO

Smiles

O=C(NCCO)CCC/C=C\C/C=C\C/C=C\C/C=C\CCCCCO

Molecular Formula

C22H37NO3

Molecular Weight

363.53

Precautions

P210-P233-P240-P241-P242-P243-P264-P280-P303+P361+P353-P305+P351+P338-P370+P378-P403+P235-P501

References & Citations

[1]Sridar C, et al. Anandamide oxidation by wild-type and polymorphically expressed CYP2B6 and CYP2D6. Drug Metab Dispos. 2011;39 (5) :782-788. |[2]Snider NT, et al. Anandamide metabolism by human liver and kidney microsomal cytochrome p450 enzymes to form hydroxyeicosatetraenoic and epoxyeicosatrienoic acid ethanolamides. J Pharmacol Exp Ther. 2007;321 (2) :590-597.