20-HETE Ethanolamide
20-HETE Ethanolamide is a metabolite of endocannabinoid Anandamide. 20-HETE Ethanolamide binds to the rat brain cannabinoid CB1 receptor with a Ki of 985 nM[1][2].
Product Specifications
CAS Number
[942069-11-6]
UNSPSC
12352211
Hazard Statement
H225-H319
Target
Endogenous Metabolite
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/20-hete-ethanolamide.html
Solubility
10 mM in DMSO
Smiles
O=C(NCCO)CCC/C=C\C/C=C\C/C=C\C/C=C\CCCCCO
Molecular Formula
C22H37NO3
Molecular Weight
363.53
Precautions
P210-P233-P240-P241-P242-P243-P264-P280-P303+P361+P353-P305+P351+P338-P370+P378-P403+P235-P501
References & Citations
[1]Sridar C, et al. Anandamide oxidation by wild-type and polymorphically expressed CYP2B6 and CYP2D6. Drug Metab Dispos. 2011;39 (5) :782-788. |[2]Snider NT, et al. Anandamide metabolism by human liver and kidney microsomal cytochrome p450 enzymes to form hydroxyeicosatetraenoic and epoxyeicosatrienoic acid ethanolamides. J Pharmacol Exp Ther. 2007;321 (2) :590-597.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
Curated Selection
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