SPSB2-iNOS inhibitory cyclic peptide-1

SPSB2-iNOS inhibitory cyclic peptide-1 is an inhibitor for the interaction of SPRY domain and SOCS-box protein 2 (SPSB2) and iNOS, through binding SPSB2 on iNOS site with KD of 4.4 nM. SPSB2-iNOS inhibitory cyclic peptide-1 is resistant to the proteases pepsin, trypsin and α-chymotrypsin. SPSB2-iNOS inhibitory cyclic peptide-1 is stable in human plasma and in oxidative environment[1].

Product Specifications

CAS Number

[1621616-13-4]

UNSPSC

12352209

Target

NO Synthase

Type

Peptides

Related Pathways

Immunology/Inflammation

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/spsb2-inos-inhibitory-cyclic-peptide-1.html

Purity

99.81

Solubility

DMSO : 50 mg/mL (ultrasonic)

Smiles

CC[C@@H]([C@@]1([H])C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CSSC[C@@H](C(N[C@H](C(N[C@H](C(N1)=O)CC(O)=O)=O)C(C)C)=O)NC(C)=O)C(N)=O)=O)CC(N)=O)=O)CC(N)=O)=O)CC(N)=O)=O)C