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Glutaric acid (Standard)

Glutaric acid (Standard) is the analytical standard of Glutaric acid. This product is intended for research and analytical applications. Glutaric acid, C5 dicarboxylic acid, is an intermediate during the catabolic pathways of lysine and tryptophan. Glutaric acid affects pericyte contractility and migration. Glutaric acid is an indicator of glutaric aciduria type I[1][2][3]. In Vitro: Glutaric acid (GA) at concentrations of 1 and 2 mM is able to reduce TRAP measurement by up to 28% in a dose-dependent manner (β=0.77; P[1].

Product Specifications

UNSPSC

12352211

Hazard Statement

H314

Target

Endogenous Metabolite; Reference Standards

Type

Reference Standards

Related Pathways

Metabolic Enzyme/Protease; Others

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/glutaric-acid-standard.html

Purity

98.44

Smiles

O=C(O)CCCC(O)=O

Molecular Formula

C5H8O4

Molecular Weight

132.12

Precautions

H314

References & Citations

[1]Yang SY, et, al. Production of glutaric acid from 5-aminovaleric acid by robust whole-cell immobilized with polyvinyl alcohol and polyethylene glycol. Enzyme Microb Technol. 2019 Sep;128:72-78.|[2]Boy N, et, al. Proposed recommendations for diagnosing and managing individuals with glutaric aciduria type I: second revision. J Inherit Metab Dis. 2017 Jan;40 (1) :75-101.|[3]Isasi E, et, al. Glutaric Acid Affects Pericyte Contractility and Migration: Possible Implications for GA-I Pathogenesis. Mol Neurobiol. 2019 Nov;56 (11) :7694-7707.

Shipping Conditions

Room Temperature

Storage Conditions

4°C, sealed storage, away from light and moisture

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-W008820R/Glutaric-acid-Standard-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-W008820R/Glutaric-acid-Standard-SDS-MedChemExpress.pdf

Scientific Category

Reference Standards

CAS Number

[110-94-1]

Available Sizes

Curated Selection

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