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FAAH inhibitor 1

Product Specifications

UNSPSC Description

FAAH inhibitor 1 (Benzothiazole analog 3) is a potent fatty acid amide hydrolase (FAAH) inhibitor with an IC50 of 18±8 nM[1].

Target Antigen

Autophagy; FAAH

Type

Reference compound

Related Pathways

Autophagy;Metabolic Enzyme/Protease;Neuronal Signaling

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/faah-inhibitor-1.html

Purity

98.91

Solubility

DMSO : 62.5 mg/mL (ultrasonic;warming;heat to 60°C)

Smiles

CC1=CC=C(N=C(C2=CC=C(NC(C3CCN(S(=O)(C4=CC=CS4)=O)CC3)=O)C=C2)S5)C5=C1

Molecular Weight

497.65

References & Citations

[1]Wang, Xueqing; Sarris, Katerina; Kage, Karen; et al. Synthesis and Evaluation of Benzothiazole-Based Analogues as Novel, Potent, and Selective Fatty Acid Amide Hydrolase Inhibitors. Journal of Medicinal Chemistry (2009), 52(1), 170-180.|[2]Meyers, Marvin J.; Long, Scott A.; Pelc, Matthew J.; et al. Discovery of novel spirocyclic inhibitors of fatty acid amide hydrolase (FAAH). Part 1: Identification of 7-azaspiro[3.5]nonane and 1-oxa-8-azaspiro[4.5]decane as lead scaffolds. Bioorganic & Medicinal Chemistry Letters (2011), 21(21), 6538-6544.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C, 3 years (Powder)

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-10862/FAAH-inhibitor-1-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-10862/FAAH-inhibitor-1-SDS-MedChemExpress.pdf

Clinical Information

No Development Reported

CAS Number

326866-17-5

Available Sizes

Curated Selection

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