Phenothiazine

Phenothiazine is an antibiotic which has insecticidal, fungicidal, antibacterial and anthelmintic activities. Phenothiazine also can be used for the research of neurological diseases[1][2].

Product Specifications

CAS Number

[92-84-2]

Product Name Alternative

Thiodiphenylamine

UNSPSC

12352005

Hazard Statement

H302, H317, H373, H410

Target

Antibiotic; Bacterial; Fungal; Parasite

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection; Neurological Disease

Assay Protocol

https://www.medchemexpress.com/phenothiazine.html

Purity

99.90

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

C12=CC=CC=C1NC3=C(C=CC=C3)S2

Molecular Formula

C12H9NS

Molecular Weight

199.28

Precautions

H302, H317, H373, H410

References & Citations

[1]Mitchell SC, et, al. The toxicity of phenothiazine. Drug Metabol Drug Interact. 1994;11 (3) :201-35.|[2]Ohlow MJ, et, al. Phenothiazine: the seven lives of pharmacology's first lead structure. Drug Discov Today. 2011 Feb;16 (3-4) :119-31.|[3]Jun-hua Xiao, et al. Xiao JH, Zhang YL, Ding LL, Feng XL, Wang JL. Effects of isoliensinine on proliferation of porcine coronary arterial smooth muscle cells induced by phenylephrine. Yao Xue Xue Bao. 2005 Feb;40 (2) :105-10.|[4]Songarj P, et al., The antioxidative, non-psychoactive tricyclic phenothiazine reduces brain damage after experimental traumatic brain injury in mice. Neurosci Lett. 2015 Jan 1;584:253-8.