Others Antibody
MEDI4212 is a humanized IgG1λ monoclonal antibody inhibitor targeting IgE. It effectively inhibits human IgE-mediated functional responses, such as calcium signaling, β-hexosaminidase release, and phagocytosis, through its receptor FcεRI. MEDI4212 prevents IgE from binding to CD23 with an IC50 of 8 nM and can be utilized in severe asthma research.
Product Specifications
Target
Others
Clonality
Monoclonal
Conjugation
Unconjugated
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Available Sizes
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