NF-κB, Interleukin Antibody
Selected Variant
GTR18775371-01
Size: 1 mg
MOR-106 (MOR12743) is a humanized anti-IL-17C IgG1 monoclonal antibody. It works by specifically binding to IL-17C, thereby inhibiting the NF-κB signaling pathway, with an IC50 of 59 pM for human IL-17C and 55 pM for mouse IL-17C. MOR-106 effectively reduces skin inflammation and related inflammatory factors in animal models of psoriasis and atopic dermatitis.
Product Specifications
Target
NF-κB, Interleukin
Clonality
Monoclonal
Conjugation
Unconjugated
Field of Research
Immunology & Inflammation, Signal Transduction
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
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