FGFR Antibody
HuGAL-FR21 is a humanized monoclonal IgG1 antibody targeting FGFR2IIIb. It effectively blocks the binding of FGF2, FGF7, and FGF10 to FGFR2IIIb and inhibits FGF-induced phosphorylation of FGFR2IIIb. Additionally, HuGAL-FR21 reduces FGFR2 expression in SNU-16 cells and demonstrates significant antitumor activity in gastric cancer xenograft models in nude mice. This compound is valuable for research in cancers such as gastric cancer.
Product Specifications
Target
FGFR
Clonality
Monoclonal
Conjugation
Unconjugated
Field of Research
Cardiovascular Research, Signal Transduction
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Available Sizes
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