Berninamycin A
Product Specifications
UNSPSC Description
Berninamycin A is a cyclic thiopeptide antibiotic first isolated from S. bernensis. It inhibits protein biosynthesis in Gram positive bacteria through binding with ribosomal subunits. Cyclic thiopeptide antibiotics, including berninamycin A, induce the transcriptional activator TipA in Streptomyces.
Target Antigen
Antibiotic; Bacterial
Type
Peptides
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/berninamycin-a.html
Smiles
O=C(C1=NC(C2=COC3=N2)=C(C4=NC(C(N[C@]([C@H](O)C)([H])C(N/C(C5=NC(C(NC(C(N[C@@H](C(C)(O)C)C(NC(C6=NC(C(NC(C(NC3=C)=O)=C)=O)=C(C)O6)=C)=O)=O)=C)=O)=C(C)O5)=C\C)=O)=O)=CS4)C=C1)NC(C(NC(C(N)=O)=C)=O)=C
Molecular Weight
1146.11
References & Citations
[1]Chiu, et al. Broad spectrum thiopeptide recognition specificity of the Streptomyces lividans TipAL protein and its role in regulating gene expression. J. Biol. Chem. 274(29), 20578-20586 (1999).
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-P2020/Berninamycin-A-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-P2020/
Clinical Information
No Development Reported
CAS Number
58798-97-3
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