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NF-κB, Others, IFNAR Antibody

MG-1131 is a human monoclonal antibody (mAb) targeting TIGIT. It activates NF-κB signaling in T cells and enhances NK cell-mediated tumor-killing activity in a PVR-dependent manner. By blocking TIGIT, MG-1131 increases IFN-γ secretion. This compound is applicable for research in antitumor immunity. Recommended isotype control: HumanIgG1kappa, Isotype Control.

Product Specifications

Target

Others, IFNAR, NF-κB

Clonality

Monoclonal

Conjugation

Unconjugated

Field of Research

Immunology & Inflammation, Signal Transduction

Storage Conditions

Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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