Gamma-secretase Antibody
MEDI0639 (21H3RK) is a human monoclonal antibody (mAb) targeting DLL4. It inhibits the interaction between Notch1 and Dll4 and reverses Notch1-mediated inhibition of in vitro human umbilical vein endothelial cell growth. Additionally, MEDI0639 enhances human angiogenesis and reduces the number of smooth muscle actin-positive mural cell-covered vessels. This compound can be used in research on small cell lung cancer and solid tumors.
Product Specifications
Target
Gamma-secretase
Clonality
Monoclonal
Conjugation
Unconjugated
Field of Research
Neuroscience, Protein Biochemistry, Stem Cell & Developmental Biology
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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