Others, PD-1/PD-L1 Antibody
IBI-322 is a bispecific antibody targeting PD-L1 and CD47. In monovalent binding, it can attenuate the activity of CD47, and in bivalent binding, it can block the activity of PD-L1. IBI-322 selectively binds to CD47+PD-L1+ tumor cells, effectively inhibiting the CD47-SIRPα signaling and inducing strong tumor cell phagocytosis in vitro.
Product Specifications
Target
Others, PD-1/PD-L1
Clonality
Recombinant
Conjugation
Unconjugated
Field of Research
Cancer Biology; Immunology & Inflammation, Cell Biology, Immunology & Inflammation
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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