TNF Antibody
AGEN-2373 is a conditional agonist antibody targeting the costimulatory receptor CD137. It binds to CD137 without interfering with ligand binding. AGEN-2373 stimulates CD137 under receptor clustering conditions and can enhance T-cell activity when used with other checkpoint modulators (e.g., PD-1 antagonists and OX40 agonists) . AGEN-2373 is used in human malignancy research.
Product Specifications
Target
TNF
Conjugation
Unconjugated
Field of Research
Cell Biology, Immunology & Inflammation
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
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