Tuberculosis inhibitor 12

Tuberculosis inhibitor 12 (compound 12) is an oxadiazole derivative and an inhibitor of Mycobacterium tuberculosis. The inhibition rates of Tuberculosis inhibitor 12 (20 μM) on 7H9-Tw-OADC and 7H9-Tw-OADC reached 82% and 78% respectively[1].

Product Specifications

CAS Number

[793729-44-9]

UNSPSC

12352005

Hazard Statement

H302, H315, H319

Target

Bacterial

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/tuberculosis-inhibitor-12.html

Purity

97.0

Solubility

DMSO : 50 mg/mL (ultrasonic)

Smiles

FC1=CC=C(C2=NN=C(CSC3=NN=C(C4=CC=CO4)O3)O2)C=C1

Molecular Formula

C15H9FN4O3S

Molecular Weight

344.32

Precautions

H302, H315, H319

References & Citations

[1]Early JV, et al. Oxadiazoles Have Butyrate-Specific Conditional Activity against Mycobacterium tuberculosis. Antimicrob Agents Chemother. 2016 May 23;60 (6) :3608-16.