Tuberculosis inhibitor 12
Tuberculosis inhibitor 12 (compound 12) is an oxadiazole derivative and an inhibitor of Mycobacterium tuberculosis. The inhibition rates of Tuberculosis inhibitor 12 (20 μM) on 7H9-Tw-OADC and 7H9-Tw-OADC reached 82% and 78% respectively[1].
Product Specifications
CAS Number
793729-44-9
UNSPSC
12352005
Hazard Statement
H302, H315, H319
Target
Bacterial
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/tuberculosis-inhibitor-12.html
Purity
97.0
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
FC1=CC=C(C2=NN=C(CSC3=NN=C(C4=CC=CO4)O3)O2)C=C1
Molecular Formula
C15H9FN4O3S
Molecular Weight
344.32
Precautions
H302, H315, H319
References & Citations
[1]Early JV, et al. Oxadiazoles Have Butyrate-Specific Conditional Activity against Mycobacterium tuberculosis. Antimicrob Agents Chemother. 2016 May 23;60 (6) :3608-16.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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