Quinolinic acid-d3
Quinolinic acid-d3 is the deuterium labeled Quinolinic acid. Quinolinic acid, an endogenous metabolite of tryptophan, is a N-methyl-D-aspartate receptor (NMDA receptor) agonist. Quinolinic acid increases glutamate efflux, induces the generation of ROS, activates nitric oxide synthase, produces excessive NO, leading to calcium ion influx and neuronal apoptosis.
Product Specifications
CAS Number
138946-42-6
UNSPSC
12352005
Target
Apoptosis; Endogenous Metabolite; iGluR; Isotope-Labeled Compounds; NO Synthase; Reactive Oxygen Species (ROS)
Type
Isotope-Labeled Compounds
Related Pathways
Apoptosis; Immunology/Inflammation; Membrane Transporter/Ion Channel; Metabolic Enzyme/Protease; Neuronal Signaling; NF-κB; Others
Field of Research
Inflammation/Immunology; Neurological Disease
Purity
99.90
Solubility
DMSO : 33.33mg/mL (ultrasonic) |H2O : 3.33mg/mL (ultrasonic)
Smiles
[2H]C1=C([2H])C([2H])=C(C(O)=O)C(C(O)=O)=N1
Molecular Formula
C7H2D3NO4
Molecular Weight
170.14
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported
Isoform
NMDA Receptor
Available Sizes
Frequently Asked Questions
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