STAT3-IN-28
STAT3-IN-28 (compound 18) is a STAT3 inhibitor. STAT3-IN-28 can inhibit the activation of microglia and has anti-neuroinflammatory effects. STAT3-IN-28 can cross the blood-brain barrier[1].
Product Specifications
UNSPSC
12352005
Target
STAT
Type
Reference compound
Related Pathways
JAK/STAT Signaling; Stem Cell/Wnt
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/stat3-in-28.html
Smiles
O=C(C1=C(O)C=C(C)C=C1)NCCC2=CNC3=CC(N(C)C)=CC=C32
Molecular Formula
C20H23N3O2
Molecular Weight
337.42
References & Citations
[1]Zhao Y, et al. N-Salicyloyl Tryptamine Derivatives as Potent Neuroinflammation Inhibitors by Constraining Microglia Activation via a STAT3 Pathway. ACS Chem Neurosci. 2024 Jul 3;15 (13) :2484-2503.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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