Zastaprazan
Zastaprazan (JP-1366) is a proton pump inhibitor and a potent potassium-competitive acid blocker. Zastaprazan can be used in the research of gastrointestinal inflammatory diseases or gastric acid-related diseases such as gastroesophageal reflux disease[1][2].
Product Specifications
CAS Number
[2133852-18-1]
Product Name Alternative
JP-1366
UNSPSC
12352005
Target
Proton Pump
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/zastaprazan.html
Concentration
10mM
Purity
99.96
Solubility
DMSO : 33.33 mg/mL (ultrasonic)
Smiles
O=C(N1CCC1)C2=CN3C(C)=C(C)N=C3C(NCC4=C(C)C=CC=C4C)=C2
Molecular Formula
C22H26N4O
Molecular Weight
362.47
References & Citations
[1]Jeongmin Kim, et al. Imidazo[1,2-a]pyridine derivatives, methods for preparing the same and use thereof. WO2018008929A1. 2018-01-11.|[2]Oh JH, et al. Randomized, Double-Blind, Active-Controlled Phase 3 Study to Evaluate Efficacy and Safety of Zastaprazan Compared With Esomeprazole in Erosive Esophagitis. Am J Gastroenterol. 2025 Feb 1;120 (2) :353-361.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Phase 3
Available Sizes
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