DTNA rabbit pAb
The protein encoded by this gene belongs to the dystrobrevin subfamily of the dystrophin family. This protein is a component of the dystrophin-associated protein complex (DPC), which consists of dystrophin and several integral and peripheral membrane proteins, including dystroglycans, sarcoglycans, syntrophins and alpha- and beta-dystrobrevin. The DPC localizes to the sarcolemma and its disruption is associated with various forms of muscular dystrophy. Mutations in this gene are associated with left ventricular noncompaction with congenital heart defects. Multiple alternatively spliced transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Jul 2008],
Product Specifications
Background
Gene ID
1837
UniProt
Q9Y4J8
Cellular Locus
Cytoplasm. Cell junction, synapse. Cell membrane. In peripheral nerves, colocalizes with MAGEE1 in the Schwann cell membrane..
Host
Rabbit
Species Reactivity
Human,Mouse
Reactivity
Human; Mouse
Immunogen
Synthesized peptide derived from human DTNA AA range: 131-181
Clonality
Polyclonal
Isotype
IgG
Source
Rabbit
Applications
WB
Validated Applications
WB
Stability
-20°C/1 year
Concentration
1 mg/mL
Dilution
WB 1: 500-2000
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Product Datasheet
https://www.elkbiotech.com/upload/file/Antibodies/pAb/ES16885-1.pdf
Subcellular Location
Cytoplasm. Cell junction, synapse. Cell membrane . In peripheral nerves, colocalizes with MAGEE1 in the Schwann cell membrane. .
Gene ID (Human)
1837
SwissProt (Human)
Q9Y4J8
Available Sizes
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