Dihexyl phthalate-3,4,5,6-d4

Dihexyl phthalate-3,4,5,6-d4 is the deuterium labeled Dihexyl phthalate-3,4,5,6. Dihexyl phthalate (HY-W011215) is one of the commonly used phthalate esters in various plastics and consumer products. Dihexyl phthalate is classified as a priority pollutant and an endocrine disruptor. Dihexyl phthalate can induce reactive oxygen species (ROS) accumulation, promote inflammation, and lead to significant increases in apoptosis and inflammation-related gene expression levels. Dihexyl phthalate can cause testicular atrophy and is a reproductive toxicant[1][2].

Product Specifications

CAS Number

[1015854-55-3]

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Apoptosis; Isotope-Labeled Compounds; Reactive Oxygen Species (ROS)

Type

Isotope-Labeled Compounds

Related Pathways

Apoptosis; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB; Others

Field of Research

Others

Purity

98.20

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

CCCCCCOC(C1=C(C([2H])=C([2H])C([2H])=C1[2H])C(OCCCCCC)=O)=O

Molecular Formula

C20H26D4O4

Molecular Weight

338.47

Precautions

H302, H315, H319, H335

References & Citations

[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216.|[2]Kim YH, et al. Enhanced degradation and toxicity reduction of dihexyl phthalate by Fusarium oxysporum f. sp. pisi cutinase. J Appl Microbiol. 2007 Jan;102 (1) :221-8.|[3]Song D, et al. Combining metabolomics with bioanalysis methods to investigate the potential toxicity of dihexyl phthalate[J]. Environmental toxicology, 2021, 36 (2) : 213-222.