Stacofylline
Stacofylline (S 9977 free base; S 9977-2 free base), a Xanthine derivative, is a potent AChE inhibitor with an IC50 of 5-50 nM. Stacofylline shows anti-amnesic and promnesic activities[1][2].
Product Specifications
CAS Number
98833-92-2
Product Name Alternative
S 9977 (free base) ; S 9977-2 (free base)
UNSPSC
12352005
Target
Cholinesterase (ChE) ; Drug Derivative
Type
Reference compound
Related Pathways
Neuronal Signaling; Others
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/stacofylline.html
Solubility
10 mM in DMSO
Smiles
CN1C2=C(N(C(N(C)C2=O)=O)C)N=C1CCCN3CCN(C(N(CC)CC)=O)CC3
Molecular Formula
C20H33N7O3
Molecular Weight
419.52
References & Citations
[1]Roger D. Porsolt, et al. Potential cognition-enhancing properties of S 9977 in three moenls of amnesia in the mouse. Drug Development Research. 1992.|[2]L E Trudeau, et al. Xanthine derivatives IBMX and S-9977-2 potentiate transmission at an Aplysia central cholinergic synapse. Brain Res. 1992 Jul 17;586 (1) :78-85.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
AChE
Available Sizes
Frequently Asked Questions
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