FX-909

FX-909 is a covalent peroxisome proliferator-activated receptor gamma (PPARG) inverse agonist. FX-909 can be used for the research of cancer[1].

Product Specifications

CAS Number

[2924573-90-8]

UNSPSC

12352005

Target

PPAR

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage; Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/fx-909.html

Concentration

10mM

Purity

99.79

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

FC1=C2C(NC(C3=C(S(C)(=O)=O)C=CC(C#N)=C3)=CC2=O)=CC(F)=C1

Molecular Formula

C17H10F2N2O3S

Molecular Weight

360.33

References & Citations

[1]Mertz J A, et al. Development of a surrogate tissue pharmacodynamic (PD) assay for clinical use with FX-909, a novel inhibitor of the urothelial luminal lineage transcription factor peroxisome proliferator-activated receptor gamma (PPARG) . Cancer Research, 2023, 83 (7_Supplement) : 2802-2802.