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Fmoc-His (Trt) -OH-15N3

Fmoc-His (Trt) -OH-15N3 is the 15N labeled Fmoc-His (Trt) -OH[1]. Fmoc-His (Trt) -OH has trityl (Trt) group to protect the side-chain of His. Fmoc-His (Trt) -OH has Fmoc group to protect -αNH2. Fmoc-His (Trt) -OH can be used for solid phase synthesis of peptides, providing protection against racemization and by-product formation[2].

Product Specifications

CAS Number

1217696-12-2

UNSPSC

12352005

Target

Amino Acid Derivatives; Isotope-Labeled Compounds

Type

Isotope-Labeled Compounds

Related Pathways

Others

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/fmoc-his-trt-oh-15n3.html

Solubility

10 mM in DMSO

Smiles

O=C(O)[C@H](CC1=C[15N](C(C2=CC=CC=C2)(C3=CC=CC=C3)C4=CC=CC=C4)C=[15N]1)[15NH]C(OCC5C6=C(C7=C5C=CC=C7)C=CC=C6)=O

Molecular Formula

C40H33 15N3O4

Molecular Weight

622.69

References & Citations

[1]Yi Y, et, al. Suppression of Simultaneous Fmoc-His (Trt) -OH Racemization and Nα-DIC-Endcapping in Solid-Phase Peptide Synthesis through Design of Experiments and Its Implication for an Amino Acid Activation Strategy in Peptide Synthesis. Org. Process Res. Dev. 2022 Jun 27.|[2]Aggarwal S, et al. [DLys (6) ]-luteinizing hormone releasing hormone-curcumin conjugate inhibits pancreatic cancer cell growth in vitro and in vivo. Int J Cancer. 2011 Oct 1;129 (7) :1611-23.|[3]Kamysz E, et al. Characterization of the effects of opiorphin and sialorphin and their analogs substituted in position 1 with pyroglutamic acid on motility in the mouse ileum. J Pept Sci. 2013 Mar;19 (3) :166-72.

Shipping Conditions

Room temperature

Scientific Category

Isotope-Labeled Compounds

Clinical Information

No Development Reported

Frequently Asked Questions

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