SLC11A2, Human (HEK293, His, MBP, FLAG)

The SLC11A2 protein is a proton-coupled metal ion symporter that selectively transports divalent metal cations, including Cd (2+), Fe (2+), Co (2+), Mn (2+), and less Significant Zn (2+), Ni (2+), VO (2+), the stoichiometric ratio of protons and metal ions is 1:1. It is critical for iron homeostasis, regulating intestinal Fe (2+) absorption, transporting TF-associated endosomal Fe (2+), and promoting Fe (2+) and Mn (2+) entry into mitochondria. SLC11A2 Protein, Human (HEK293, His, MBP, FLAG) is the recombinant human-derived SLC11A2 protein, expressed by HEK293 , with N-MBP, C-Flag, N-8*His labeled tag.