Praeruptorin B
Praeruptorin B is an inhibitor of sterol regulatory element-binding proteins (SREBPs) .
Product Specifications
CAS Number
[73069-28-0]
Product Name Alternative
Praeruptorin D
UNSPSC
12352005
Hazard Statement
H302, H315, H319
Target
Fatty Acid Synthase (FASN)
Type
Natural Products
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/Praeruptorin_B.html
Purity
99.95
Solubility
DMSO : 25 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=C1C=CC2=CC=C3C([C@H](OC(/C(C)=C\C)=O)[C@H](OC(/C(C)=C\C)=O)C(C)(C)O3)=C2O1
Molecular Formula
C24H26O7
Molecular Weight
426.46
Precautions
H302, H315, H319
References & Citations
[1]Zu-Guo Zheng, et al. Praeruptorin B improves diet-induced hyperlipidemia and alleviates insulin resistance via regulating SREBP signaling pathway. RSC Adv., 2018, 8, 354–366|[2]Liu X, et al. The Inhibition of UDP-Glucuronosyltransferase (UGT) Isoforms by Praeruptorin A and B. Phytother Res. 2016 Nov;30 (11) :1872-1878.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Available Sizes
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