Praeruptorin B

Praeruptorin B is an inhibitor of sterol regulatory element-binding proteins (SREBPs) .

Product Specifications

CAS Number

[73069-28-0]

Product Name Alternative

Praeruptorin D

UNSPSC

12352005

Hazard Statement

H302, H315, H319

Target

Fatty Acid Synthase (FASN)

Type

Natural Products

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/Praeruptorin_B.html

Purity

99.95

Solubility

DMSO : 25 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

O=C1C=CC2=CC=C3C([C@H](OC(/C(C)=C\C)=O)[C@H](OC(/C(C)=C\C)=O)C(C)(C)O3)=C2O1

Molecular Formula

C24H26O7

Molecular Weight

426.46

Precautions

H302, H315, H319

References & Citations

[1]Zu-Guo Zheng, et al. Praeruptorin B improves diet-induced hyperlipidemia and alleviates insulin resistance via regulating SREBP signaling pathway. RSC Adv., 2018, 8, 354–366|[2]Liu X, et al. The Inhibition of UDP-Glucuronosyltransferase (UGT) Isoforms by Praeruptorin A and B. Phytother Res. 2016 Nov;30 (11) :1872-1878.