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PKR1 antagonist 1

PKR1 antagonist 1 (PC1) is a potent PKR1 antagonist. PKR1 antagonist 1 reduces hyperalgesia and allodynia in SNI mice[1].

Product Specifications

CAS Number

910113-60-9

UNSPSC

12352005

Target

Prokineticin Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/pkr1-antagonist-1.html

Smiles

O=C1N=C(N(CC2=CC=C(C=C2)OC)C(N1CC3=CC=C(CC)C=C3)=O)NCCNC(N)=N

Molecular Formula

C23H29N7O3

Molecular Weight

451.52

References & Citations

[1]Guida F, et al. PC1, a non-peptide PKR1-preferring antagonist, reduces pain behavior and spinal neuronal sensitization in neuropathic mice. Pharmacol Res. 2015 Jan;91:36-46.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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