H-2 Kb/Db mAb (28-8-6S), InVivoPure

The anti-H-2 Kb/Db monoclonal antibody (clone 28-8-6S) was purified from supernatant of HB-51TM 28-8-6S from the ATCC.* Clone 28-8-6S is a mouse monoclonal antibody that specifically binds to the murine MHC class I molecules H-2Kb and H-2Db, which are part of the H-2b haplotype commonly found in C57BL/6 mice. These molecules are essential for presenting endogenous peptides to CD8+ cytotoxic T lymphocytes, playing a central role in immune surveillance and response to infection and cancer. H-2Kb and H-2Db are critical for presenting intracellular antigens to CD8+ T cells. This antibody is widely used in immunological research, including studies on viral immunity, tumor immunology , and neuroimmune interactions. It is also valuable in transgenic mouse models and vaccine development. This antibody has been reported to be used in immunofluorescence, immunohistochemistry, and flow cytometry.