H-2kd/H-2D mAb (34-1-2S), InVivoPure

The anti-H2Kd/H-2Dd monoclonal antibody (clone 34-1-2S) is a mouse-derived antibody that targets MHC class I alloantigens, specifically H-2Kd and H-2Dd. These antigens are expressed on the surface of nucleated cells in mice with the H-2Kd/H-2Dd haplotype [1]. The antibody is critical for antigen presentation to T cells expressing CD3/TCR and CD8 proteins [2]. This antibody is known for its cross-reactivity with other MHC class I alloantigens, including those of the H-2Kb, H-2Ks, H-2Kr, H-2Kq, and H-2Kp haplotypes [3]. It is commonly used in flow cytometry for the analysis of mouse splenocytes and other cell types. This antibody is a valuable tool for researchers studying immune responses by helping to identify and characterize cells based on their MHC class I expression.