NK1.1 mAb (PK136), InVivoPure
The PK136 monoclonal antibody is a widely used mouse IgG2a antibody that specifically recognizes NK1.1, a surface glycoprotein belonging to the NKR-P1 (CD161) family. This Marker is expressed on NK cells and NKT cells in certain mouse strains including C57BL/6, FVB/N and NZB. Due to its specificity, PK136 is extensively used in immunological research to study NK cell biology, innate immunity, and tumor immunology. The PK136 antibody binds to NKR-P1C (NK1.1) on NK cells and a subset of T cells known as NKT cells in NK1.1-expressing strains. It does not cross-react with NK cells from BALB/c or other NK1.1-negative strains. In addition to Flow and IHC, this clone has also been reported to work for in-vitro and in-vivo depletion assays.
Product Specifications
Product Name Alternative
UniProt
P27814
Reactivity
Mouse
Immunogen
Spleen enriched for NK1+ cells and bone marrow cells from CE mice
Target
NK1.1
Clonality
Monoclonal
Clone
PK136
Conjugation
Unconjugated
Concentration
≥ 1 mg/ mL
Purity
≥ 90 % (CGE, reducing conditions) ≤ 10 % aggregates (analytical SEC) Endotoxin level ≤ 2 EU/mg
Form
Clear Liquid, PBS, pH 7.4, 0.2 μm sterile filtered
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Applications Notes
Recomended Isotype: Mouse IgG2A k Isotype Control, Recomended Isotype Catalog: orb2568794
Host or Source
Mouse
Isotype
M IgG2a
Available Sizes
Frequently Asked Questions
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