Aspidin BB
Aspidin BB is a phloroglucinol derivative, which can be isolated from the aerial part of Dryopteris championii. Aspidin BB has anticancer activity. Aspidin BB induces cell cycle arrest and apoptosis in human ovarian HO-8910 cells[1][2].
Product Specifications
CAS Number
584-28-1
UNSPSC
12352005
Target
Apoptosis; Bcl-2 Family; Caspase
Type
Natural Products
Related Pathways
Apoptosis
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/aspidin-bb.html
Purity
98.02
Solubility
DMSO : 12.5 mg/mL (ultrasonic)
Smiles
CCCC(C1=C(C(C)(C)C(O)=C(CC2=C(O)C(C(CCC)=O)=C(OC)C(C)=C2O)C1=O)O)=O
Molecular Formula
C25H32O8
Molecular Weight
460.52
References & Citations
[1]Sun Y, et al. Aspidin BB, a phloroglucinol derivative, induces cell cycle arrest and apoptosis in human ovarian HO-8910 cells. Chem Biol Interact. 2013 Jul 5;204 (2) :88-97.|[2]Chen NH, et al. Drychampones A-C: Three Meroterpenoids from Dryopteris championii. J Org Chem. 2016 Oct 7;81 (19) :9443-9448.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
Bax; Bcl-2; Caspase 3
Available Sizes
Frequently Asked Questions
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