Aspidin BB

Aspidin BB is a phloroglucinol derivative, which can be isolated from the aerial part of Dryopteris championii. Aspidin BB has anticancer activity. Aspidin BB induces cell cycle arrest and apoptosis in human ovarian HO-8910 cells[1][2].

Product Specifications

CAS Number

[584-28-1]

UNSPSC

12352005

Target

Apoptosis; Bcl-2 Family; Caspase

Type

Natural Products

Related Pathways

Apoptosis

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/aspidin-bb.html

Purity

98.02

Solubility

DMSO : 12.5 mg/mL (ultrasonic)

Smiles

CCCC(C1=C(C(C)(C)C(O)=C(CC2=C(O)C(C(CCC)=O)=C(OC)C(C)=C2O)C1=O)O)=O

Molecular Formula

C25H32O8

Molecular Weight

460.52

References & Citations

[1]Sun Y, et al. Aspidin BB, a phloroglucinol derivative, induces cell cycle arrest and apoptosis in human ovarian HO-8910 cells. Chem Biol Interact. 2013 Jul 5;204 (2) :88-97.|[2]Chen NH, et al. Drychampones A-C: Three Meroterpenoids from Dryopteris championii. J Org Chem. 2016 Oct 7;81 (19) :9443-9448.