(±)-Evodiamine
Product Specifications
UNSPSC Description
(±)-Evodiamine, a quinazolinocarboline alkaloid, is a Top1 inhibitor. Evodiamine exhibits anti-inflammatory, antiobesity, and antitumor effects. (±)-Evodiamine inhibits the proliferation of a wide variety of tumor cells by inducing their apoptosis[1].
Target Antigen
Apoptosis; Topoisomerase
Type
Natural Products
Related Pathways
Apoptosis;Cell Cycle/DNA Damage
Applications
COVID-19-anti-virus
Field of Research
Cancer; Inflammation/Immunology; Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/racemic-evodiamine.html
Purity
99.97
Solubility
DMSO : 10 mg/mL (ultrasonic;warming;heat to 60°C)
Smiles
O=C1C2=CC=CC=C2N(C)C(N1CC3)C4=C3C5=CC=CC=C5N4
Molecular Weight
303.36
References & Citations
[1]Dong G, et, al. New tricks for an old natural product: discovery of highly potent evodiamine derivatives as novel antitumor agents by systemic structure-activity relationship analysis and biological evaluations. J Med Chem. 2012 Sep 13;55(17):7593-613.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-N0114A/racemic-Evodiamine-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-N0114A/racemic-Evodiamine-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
518-18-3
Available Sizes
Curated Selection
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