BSJ-04-122
BSJ-04-122 is a covalent MKK4/7 dual inhibitor. BSJ-04-122 inhibits MKK4 and MKK7 with IC50 values of 4 nM and 181 nM, respectively. BSJ-04-122 can be used for the research of cancer[1].
Product Specifications
CAS Number
[2513289-74-0]
UNSPSC
12352005
Hazard Statement
H302-H315-H319
Target
P38 MAPK
Type
Reference compound
Related Pathways
MAPK/ERK Pathway
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/bsj-04-122.html
Purity
99.86
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
C=CC(NC1=CC=CC=C1NC2=C3C(NC=C3Cl)=NC=N2)=O
Molecular Formula
C15H12ClN5O
Molecular Weight
313.74
Precautions
P264-P270-P280-P302+P352-P305+P351+P338-P330-P362+P364-P501
References & Citations
[1]Jie Jiang, et al. Discovery of Covalent MKK4/7 Dual Inhibitor. Cell Chem Biol
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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