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BSJ-04-122

BSJ-04-122 is a covalent MKK4/7 dual inhibitor. BSJ-04-122 inhibits MKK4 and MKK7 with IC50 values of 4 nM and 181 nM, respectively. BSJ-04-122 can be used for the research of cancer[1].

Product Specifications

CAS Number

[2513289-74-0]

UNSPSC

12352005

Hazard Statement

H302-H315-H319

Target

P38 MAPK

Type

Reference compound

Related Pathways

MAPK/ERK Pathway

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/bsj-04-122.html

Purity

99.86

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

C=CC(NC1=CC=CC=C1NC2=C3C(NC=C3Cl)=NC=N2)=O

Molecular Formula

C15H12ClN5O

Molecular Weight

313.74

Precautions

P264-P270-P280-P302+P352-P305+P351+P338-P330-P362+P364-P501

References & Citations

[1]Jie Jiang, et al. Discovery of Covalent MKK4/7 Dual Inhibitor. Cell Chem Biol

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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