TRPA1-IN-2
TRPA1-IN-2 (compound 1) is a potent and orally active TRPA1 inhibitor with an IC50 value of 0.04 µM. TRPA1-IN-2 shows anti-inflammation activity[1].
Product Specifications
CAS Number
[2415206-22-1]
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
TRP Channel
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/trpa1-in-2.html
Concentration
10mM
Purity
99.82
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
N#CC1=CC=C(NC2(CCCC2)C(N3CCN(CC3)C4=CC=C(C(F)(F)F)C=C4)=O)C=C1
Molecular Formula
C24H25F3N4O
Molecular Weight
442.48
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
References & Citations
[1]YunFeng Cheng, et al. Heteroaromatic acetamide derivative, and preparation and use thereof. WO2020244460A1.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
TRPA1
Available Sizes
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