HnRNPK-IN-1
HnRNPK-IN-1 is a heterogeneous nuclear ribonucleoprotein K (hnRNPK) binding ligand with Kd values of 4.6 μM and 2.6 μM measured with SPR and MST, respectively. hnRNPK-IN-1 inhibits c-myc transcription by disrupting the binding of hnRNPK and c-myc promoter. hnRNPK-IN-1 induces Hela cells apoptosis and has strongly anti-tumor activities[1].
Product Specifications
CAS Number
[2313528-04-8]
UNSPSC
12352005
Target
Apoptosis; c-Myc
Type
Reference compound
Related Pathways
Apoptosis
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/hnrnpk-in-1.html
Purity
97.0
Solubility
DMSO : 5 mg/mL (ultrasonic; warming; heat to 80°C)
Smiles
O=C(C1=CC=C(OC)C=C1)/C=C/C2=NC3=CC=C([N+]([O-])=O)C=C3C(N4CCOCC4)=C2
Molecular Formula
C23H21N3O5
Molecular Weight
419.43
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Explore Other Products
Browse additional items from our catalog
Haematoxylin Stain Certified C.l. No. 75290 For Microscopy 95.0%
Haematoxylin Stain Certified C.l. No. 75290 For Microscopy 95.0%
CHK1 (S280) (Serine/Threonine-protein Kinase Chk1, CHEK1) (FITC)
CHK1 (S280) (Serine/Threonine-protein Kinase Chk1, CHEK1) (FITC)
