GPR40 agonist 4
GPR40 agonist 4 is a potent free fatty acid receptor 1 (FFA1/ GPR40) agonist with a pEC50 of 7.54.
Product Specifications
CAS Number
2102196-57-4
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
Free Fatty Acid Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/FAA1_agonist-1.html
Concentration
10mM
Purity
98.38
Solubility
DMSO : 160 mg/mL (ultrasonic; warming)
Smiles
ClC1=CC=CC=C1C2=CC(COC3=CC=C(S(CC(O)=O)(=O)=O)C=C3)=CC=C2
Molecular Formula
C21H17ClO5S
Molecular Weight
416.87
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
[1]Li Z, et al. Discovery of phenylsulfonyl acetic acid derivatives with improved efficacy and safety as potent free fatty acid receptor 1 agonists for the treatment of type 2 diabetes. Eur J Med Chem. 2017 Sep 29;138:458-479.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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